All Solid Tumors

Cancer Type

Tumor Tissue (FFPE)

Specimen Requirements

8 Working Days

Turnaround Time ¹

ACTDrug®+ is an NGS-based test, which sequences 40 druggable genes, 13 fusion genes, and more than 350 fusion transcripts simultaneously from cancer specimens.

Targeted Cancer Genomic Profiling Service

40

Cancer Genes

13

Fusion Genes

350

Fusion Transcripts

View Gene List

Hallmarks

Drug-Target-Based Panel

Sequences 40 actionable genes,13 fusion genes and more than 350 fusion transcripts with genetic alterations.

Short Turnaround Time

Provides professional solutions within 8 working days (starting from the date of receipt of approved samples at our CAP-accredited laboratory).

High Sensitivity

Uses the NGS platform for microscale specimens.

Tailored Drug Options

Analyzes single nucleotide variation (SNV), small insertion/deletion (InDel), copy number variation (CNV)and fusion gene to provide tailored drug options.

Pioneering Bioinformatics

Integrates cancer biology, medical biology, molecular biology, cell biology, immunology, bioinformatics, data science and pharmaceutical biology to provide insightful interpretation of the data analyses.

Summary

Select Drugs for Your Cancer Patient

Provides tailored drug options through precise genomic profiling for important actionable genes.

A Precise Choice for Cancer Genomic Profiling

ACTDrug®+ is a next-generation sequencing (NGS)-based assay, which sequences 40 actionable genes, 13 fusion genes and more than 350 fusion transcripts simultaneously from cancer specimens in our CAP-accredited laboratory. This assay is specially designed for patients with breast, lung, colorectal or gastric cancers, providing tailored genomic profiling and recommendations of targeted drugs approved by the US FDA.

Explore Various Genetic Alterations for More Precise Therapeutic Implication

ACTDrug®+ performs various genetic variation analyses. In addition to single nucleotide variation (SNV) and small insertion/ deletion (InDel), it provides copy number variation (CNV) analysis for 22 genes and fusion gene detection for more precise determination of potential implications.

For All Solid Tumors

Selects the most suitable treatment for newly diagnosed patients based on actionable genetic mutations.

Precise Reporting

Considers targeted therapies and hormonal therapies approved by US FDA or in clinical trials.

Technical Specifications

Next Generation Sequencing (NGS)

40 actionable genes

Specimen Requirements2

Tumor tissue (FFPE)

Sequencing Mean Depth

≥ 800 x

Hotspots

>3800

ACTFusion™

Comprehensive testing of 13 fusion genes and more than 350 fusion transcripts

Documentation

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Gene List

Search
Cancer Type
FDA-approved & NCCN-guided Genes

AKT1

Breast

SNV / Indel

ALK

Lung

Skin

Thyroid

SNV / Indel

CNA

Fusion

AR

No items found.

SNV / Indel

CNA

BRAF

Brain

Colorectal

Gastric

Lung

Skin

SNV / Indel

CNA

Fusion

CCND1

No items found.

SNV / Indel

CNA

CDK4

No items found.

SNV / Indel

CNA

CDK6

No items found.

SNV / Indel

CNA

CDKN2A

Brain

SNV / Indel

CNA

CTNNB1

No items found.

SNV / Indel

EGFR

Brain

Lung

SNV / Indel

CNA

Fusion

ERBB2

Breast

Colorectal

Gastric

Lung

Biliary Tract

SNV / Indel

CNA

ERBB4

No items found.

SNV / Indel

CNA

ESR1

Breast

SNV / Indel

CNA

FGFR1

Brain

SNV / Indel

CNA

Fusion

FGFR2

Biliary Tract

Brain

Pancreas

SNV / Indel

Fusion

FGFR3

Bladder

Brain

SNV / Indel

Fusion

HRAS

No items found.

SNV / Indel

IDH1

Brain

Biliary Tract

SNV / Indel

IDH2

Brain

SNV / Indel

JAK1

No items found.

SNV / Indel

JAK2

No items found.

SNV / Indel

JAK3

No items found.

SNV / Indel

KDR

No items found.

SNV / Indel

CNA

KIT

Thyroid

SNV / Indel

CNA

KRAS

Colorectal

Lung

Biliary Tract

SNV / Indel

CNA

MAP2K1

No items found.

SNV / Indel

MAP2K2

No items found.

SNV / Indel

MET

Lung

SNV / Indel

CNA

Fusion

NRAS

Colorectal

SNV / Indel

CNA

NRG1

Lung

Biliary Tract

Pancreas

Fusion

NTRK1

Brain

Breast

Colorectal

Gastric

Lung

SNV / Indel

Fusion

NTRK2

Brain

Breast

Colorectal

Gastric

Lung

SNV / Indel

Fusion

NTRK3

Biliary Tract

Bladder

Ovary

Pancreas

Prostate

SNV / Indel

Fusion

PDGFRA

No items found.

SNV / Indel

CNA

PIK3CA

Breast

Colorectal

SNV / Indel

CNA

PTEN

Breast

Colorectal

SNV / Indel

CNA

RB1

No items found.

SNV / Indel

CNA

RET

Brain

Breast

Colorectal

Ovary

Prostate

SNV / Indel

Fusion

ROS1

Lung

Pancreas

SNV / Indel

Fusion

TP53

Brain

Breast

SNV / Indel

CNA

UGT1A1

No items found.

SNV / Indel

Full Gene List

SNV / Indel

CNA

Fusion

LGR

*Genes also provide exon-skipping alteration information.

AKT1

SNV / Indel

ALK

SNV / Indel

CNA

Fusion

AR

SNV / Indel

CNA

BRAF

SNV / Indel

CNA

Fusion

CCND1

SNV / Indel

CNA

CDK4

SNV / Indel

CNA

CDK6

SNV / Indel

CNA

CDKN2A

SNV / Indel

CNA

CTNNB1

SNV / Indel

EGFR

SNV / Indel

CNA

Fusion

ERBB2

SNV / Indel

CNA

ERBB4

SNV / Indel

CNA

ESR1

SNV / Indel

CNA

FGFR1

SNV / Indel

CNA

Fusion

FGFR2

SNV / Indel

Fusion

FGFR3

SNV / Indel

Fusion

HRAS

SNV / Indel

IDH1

SNV / Indel

IDH2

SNV / Indel

JAK1

SNV / Indel

JAK2

SNV / Indel

JAK3

SNV / Indel

KDR

SNV / Indel

CNA

KIT

SNV / Indel

CNA

KRAS

SNV / Indel

CNA

MAP2K1

SNV / Indel

MAP2K2

SNV / Indel

MET

SNV / Indel

CNA

Fusion

NRAS

SNV / Indel

CNA

NRG1

Fusion

NTRK1

SNV / Indel

Fusion

NTRK2

SNV / Indel

Fusion

NTRK3

SNV / Indel

Fusion

PDGFRA

SNV / Indel

CNA

PIK3CA

SNV / Indel

CNA

PTEN

SNV / Indel

CNA

RB1

SNV / Indel

CNA

RET

SNV / Indel

Fusion

ROS1

SNV / Indel

Fusion

TP53

SNV / Indel

CNA

UGT1A1

SNV / Indel

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Disclaimers / Footnotes

  1. Turnaround time starts from the date of receipt of approved samples at our CAP-accredited laboratory.
  2. Please refer to our specimen instructions.

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