All Major Solid Tumors
Cancer Type
Blood
Sample Type
12 Working Days
Turnaround Time ¹
ACTRisk™ hereditary gene testing decodes 67 cancer genes associated with 9 common hereditary cancers and 11 cancer syndromes, which provides additional information to a health management strategy.
Precision Medicine to Plan Better Treatment
Every cancer is associated with a unique combination of genomic changes. Furthermore, different cells within a tumor may harbor different genomic abnormalities. Comprehensive genomic profiling can identify such changes in cell signaling pathways by detecting prognostic and predictive biomarkers. This information can then be used to facilitate treatment decisions. This process is known as precision medicine.
Why ACT Genomics?
Humane Process
Only a small specimen is required for the simultaneous detection of 67 genes.
Ideal Treatment
Uses genomic information for prevention measures.
Smart Budgeting
Nominates proper targeted options, immunotherapy, chemotherapy, or hormonal therapy.
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Why does cancer occur?
Cancer is caused by changes in a cell’s DNA — its genetic “blueprint.” The majority of these changes occur from external influences, known as environmental factors. However, approximately 5–10% of all cancers are caused by inherited genetic mutations passed down from our parents.
How is an hereditary cancer gene inherited?
Using hereditary breast and ovarian cancer syndrome (HBOCS) as an example, BRCA1 mutations are inherited in an autosomal dominant fashion (Figure 1). As such, each child would have a 50% chance of carrying the mutant BRCA1 gene from a parent, which predisposes them to the development of hereditary cancers. Therefore, the occurrence rate of such cancers in the affected family would be higher than that in a non-affected family. The onset of these cancers may also be earlier compared to the average age of onset of the respective cancers.
Do You Need to Prevent Cancer by Gene Testing?
To know or not to know, that is a question. Some people consider that there are no drugs for inherited genetic variants before the cancer is formed, which causes a significant mental burden; because 5-10% of cancers are caused by inherited genetic variants, if you have a family history of cancer, you are at a high risk of developing cancer. Therefore, knowing which inherited genetic variants you have may help you organize a better health management strategy. There are many inherited genetic variants known for several cancers, including BRCA1/2 genes. People carrying inherited genetic variants have a higher lifetime risk of cancer, up to 90 times higher than someone without a mutation.
More Comprehensive Diagnostic Solutions Than Traditional Hereditary Gene Testing
Through next-generation sequencing (NGS), ACTRisk™ hereditary gene testing decodes 67 cancer genes associated with 9 common hereditary cancers and 11 cancer syndromes, to provide more information for your health management strategy.
Who Is Suitable for ACTRisk™?
- Multiple family members who have cancer
- Any individual who is concerned about the inherent risk of hereditary cancers and cancer syndromes
- A family member who has multiple cancers, an early-onset cancer, or a rare cancer
Each hereditary cancer has different characteristics. It is therefore highly recommended that genetic counseling is conducted by a qualified professional before and after taking a genetic test.
Documentation
Disclaimers / Footnotes
- Turnaround time starts from the date of receipt of approved samples at our CAP-accredited laboratory.
