Lung Cancer

Cancer Type

Tumor Tissue (FFPE) or Blood

Specimen Requirements

2-3 Working Days

Turnaround Time ¹

ACT EGFR™ analyze EGFR gene mutations in cell-free DNA or FFPE DNA for non-small cell lung patients.

Droplet Digital™ PCR technology

7

Alleles

>99%

Analytical Specificity& Sensitivity

0.5%

Limit of Detection

Hallmarks of ACT EGFR™

• Plasma ddPCR detects EGFR mutationrapidly with the high specificityneeded to select therapy and avoid repeat biopsies.

• ddPCR canbe used to detect plasma EGFR gene inadvanced lung adenocarcinoma patients with higher sensitivity andspecificity compared to qPCR.

• ddPCRshowes high concordance with NGS in determiningcfDNA EGFR mutations.

Why using Droplet Digital PCR?

• Analyticalspecificity: >99%; Analytical sensitivity: >99%

•Limitof detection:0.5% of mutations in tumor

•Absolutequantification of mutant variants is allowed

• Mutantallele frequency (MAF, %) is reported.*

Summary

Technical Specifications

Documentation

Brochure
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Disclaimers / Footnotes

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